How to Fix the usb2ser.sys Error - Unable to Enable Core Isolation

Troubleshooting the usb2ser.sys Error and Core Isolation Issues

Encountering the usb2ser.sys error can prevent you from enabling the crucial Core Isolation Memory Integrity feature in Windows, leaving your system vulnerable. This guide details troubleshooting steps to resolve this issue. usb2ser.sys, developed by MediaTek Inc., is a driver file located in C:\Windows\System32\DRIVERS (or potentially within subfolders like DriverStore). Its proper functioning is vital for Core Isolation.

Several factors can trigger usb2ser.sys related memory integrity problems:

• Driver Incompatibility: The installed driver may clash with your system.
• Outdated Driver: An outdated driver can cause conflicts.
• System File Corruption: Damaged system files can lead to errors.
• Missing or Damaged Driver Files: Essential driver components might be missing or corrupted.

Before attempting solutions, a system restart is recommended. If the problem persists, try these fixes:

Solution 1: Update the Driver

1. Navigate to Start > Settings > Update & Security > Windows Update > View optional updates.
2. Expand Driver updates, select available usb2ser.sys updates (if any), and click Download and install.
3. Restart your computer to see if Core Isolation is now enabled.

Solution 2: Rename the usb2ser.sys File

This involves renaming the file to prevent it from loading. You might need administrator privileges.

1. Open File Explorer and locate usb2ser.sys in C:\Windows\System32\drivers or C:\Windows\System32\DriverStore.
2. Right-click and rename the file (e.g., usb2serold.sys). If access is denied, you may need to take ownership of the folder first. Refer to online resources for instructions on gaining full control if needed.

Solution 3: Run an SFC Scan

This checks for and repairs corrupted system files.

1. Search for Command Prompt, right-click, and select Run as administrator.
2. Type sfc /scannow and press Enter.
3. Restart your computer after the scan completes.

Solution 4: Uninstall and Delete the usb2ser.sys Driver

This is a more drastic measure, only to be used if other solutions fail.

1. Right-click the Start menu and select Device Manager.
2. Click View > Show hidden devices.
3. Locate the usb2ser.sys related driver, right-click, and select Uninstall device. Follow on-screen instructions.
4. Open File Explorer, locate and delete usb2ser.sys (if it still exists).
5. Restart your computer.

Final Thoughts:

If Core Isolation remains disabled, try the above solutions sequentially. Remember to back up your important data before making significant system changes. If the problem persists after trying all these steps, consider seeking further assistance from Microsoft support or other technical resources.

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