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What database is GTEx?

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小老鼠Original
2024-04-13 00:09:161437browse

GTEx is a comprehensive database containing gene expression data from human tissue samples. Its content includes RNA sequences, eQTL data and other relevant information from 53 tissue types. Uses include understanding tissue-specific gene expression, identifying disease-related genes, studying gene regulation and developing personalized medicine.

What database is GTEx?

What is GTEx database?

GTEx (Gene Expression Histology) database is a comprehensive resource containing gene expression data and related information for human tissue samples.

Database content:

The GTEx database collects samples from more than 700 donors, covering 53 tissue types, including all major organs and tissues. The samples were organized into over 15,000 RNA sequence (RNA-Seq) and microarray data sets.

Data type:

  • Gene expression: Records the expression level of genes in each tissue.
  • eQTL data: Identifies specific genetic variants that affect gene expression.
  • Other relevant data: Includes histological information, clinical phenotype and transcriptomic information.

Purpose:

The GTEx database provides a valuable resource for biomedical research. It can be used to:

  • Understand tissue-specific gene expression:Determine the expression patterns of different genes in different tissue types.
  • Identify disease-related genes: Identify disease-related genes by comparing gene expression in disease patients and healthy individuals.
  • Study gene regulation: Use eQTL data to study the genetic factors that affect gene expression.
  • Develop personalized medicine: Develop treatments that target specific tissues by analyzing tissue-specific gene expression.

Data access:

Data from the GTEx database can be obtained for free from its official website. Users can filter datasets by tissue type, genes, or other metadata.

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