Flexible brain-computer interface overall solution: Brain Tiger Technology strives to create

Brain Tiger Technology’s “flexible brain-computer interface overall solution” is an end-to-end solution, including flexible electrodes, surgical robots, implantable EEG collectors, EEG chips, and high-frequency digital EEG Graph machine, software algorithm cloud platform, etc. This solution is specially created by Naohu Technology for the scientific research and medical markets

What needs to be rewritten is: 1. Flexible electrode

There are three main types of flexible electrodes: tungsten wire-assisted deep flexible electrodes, fibroin deep flexible electrodes and flexible cortical electrodes. These flexible electrodes are made from medical devices combined with MEMS technology and feature high density, high throughput, low trauma and ultra-thin technology, and are very fit. Unlike traditional semi-manual processes, the increased channel count of these electrodes enables rapid iteration

The rewritten content is as follows: Tungsten wire-assisted deep flexible electrode has the ability to record Spike signals and LFP signals simultaneously. Compared with the Utah electrode, this electrode has excellent mechanical properties after being implanted in the skull, and can perfectly match the brain tissue, avoiding the displacement and mutual shearing between the brain tissue and the electrode caused by brain movement. This enables the activity of the same neuron to be tracked over time. In addition, the electrode has more channels in a single device and has multiple detection sites distributed longitudinally, which can collect three-dimensional high-density EEG signals, thereby promoting precise and smooth mind-controlled movements

Silk protein deep flexible electrode has the characteristics of good mechanical compliance, biocompatibility, controllable degradation, safety and non-toxicity. After being wrapped with silk protein, its hardness is between blood vessels and brain tissue, and it can automatically It avoids blood vessels and facilitates implantation, and at the same time, it can remain relatively static in the brain tissue. Combining silk protein with multifunctional flexible electrodes can record electrophysiological signals while providing other functions such as light and drug delivery

Flexible cortical electrodes have the characteristics of high flux, high density and high flexibility. This kind of electrode can support cortical EEG recording of up to 529 channels, with a density of 43 channels/cm², and an electrode sheet size of 43 mm × 45 mm, which can reduce surgical trauma while ensuring high throughput. In addition, the thickness of the electrode is only 20 microns, and its ultra-thin and ultra-high flexibility enables the electrode to achieve good conformal contact with brain tissue

2. Robotic Surgery

There are two types of brain tiger technology surgical robots: medical surgical robot and scientific research surgical robot. Skull window opening, brain region positioning, electrode operation and implantation are its main functions.

The medical version of the surgical robot has a high-precision multi-level precision vision module design, deep learning combined with binocular positioning, intelligent identification, and precise locking; with the help of a 5+1 degree of freedom robotic arm, it can cover the skull in a wide range and in all directions, with end movements up to 5g Acceleration, easier to control; multi-modal sensing detection enables automatic and safe stop of the skull opening; compatible with tungsten needle puncture flexible electrodes and silk protein electrode operations. It is suitable for implanting high-density flexible electrodes one by one in medical scenarios.

The scientific version of the surgical robot uses a force sensor + electric cranial drill combination to automatically open the skull; combined with binocular vision and laser scanning, it can automatically identify the skull surface and achieve automatic brain region positioning; it uses the standard rat and mouse brain positioning atlas. The 3D brain area model is used to optimize the calculation of surgical paths; combined with a 6-axis robotic arm and an electric implanter, it can realize automatic and precise implantation of electrodes; at the same time, it also has a unified interface quick-change device that can freely switch between cranial drill and implantation instruments, fiber optics, and microsyringes. This robot is suitable for experiments on rats and mice in scientific research scenarios, including operations such as cranial window opening, fiber optic implantation, virus injection, and flexible electrode implantation assisted by rigid electrodes, hardened electrodes, or tungsten needles

3. Implantable EEG collector

The implantable EEG collector is composed of electrode sheets, circuit boards, circuit board protective shells and outer shells. It is partially implanted into the brain through surgical craniotomy, the shell is fixed on the skull, and the EEG signals are conducted to the circuit board inside the shell through the electrode array, thereby realizing the extraction of the EEG signals

Implantable EEG collectors are mainly used to collect and monitor EEG signals. It mainly meets the needs of patients with ALS and helps them decode language and movements by collecting EEG signals to promote language communication and daily life assistance for patients

4． chip

"Brain-computer interface chip with tens of thousands of channels" is a professional acquisition chip serving brain-computer interface equipment. The chip is uniquely innovative in terms of the number of signal acquisition channels, the chip's hierarchical architecture design, amplifier circuit design, packaging design and hardware solutions. The main body is composed of 16384 amplifier arrays, which can amplify tiny brainwave signals about 90 times, and has a filtering function. It also supports the analog SPI protocol to output the collected data at high speed.

This product is mainly used in domestic scientific research institutes, universities and other laboratories to collect animal brain wave signals for brain-computer interface and neuroscience research. Brain Tiger Technology has successfully completed the manufacturing of independently developed EEG signal collection chips with tens of thousands of channels, and is currently developing EEG collection chips for the next generation

The content that needs to be rewritten is: 5. High-frequency digital electroencephalography machine

The high-frequency digital EEG machine is an important part of the EEG data acquisition end of the implantable brain-computer interface system. It has the core product advantages of high bandwidth, high sampling rate and high throughput. The overall design meets the requirements of medical devices and can effectively ensure the safety of use. This product supports up to 2048 channels and can collect and analyze multiple types of EEG signals in real time, including ECoG, LFP, and Spike. It is not only compatible with the flexible cortical electrodes and deep electrodes developed by Naohu Technology, but also adapts to traditional ECoG electrodes and SEEG electrodes. Mainly used in scenarios such as decoding movement intentions, language output, emotional states and other brain-computer interface data

6. Software Algorithm Cloud Platform

MindExplorer is an scalable open platform independently developed by Brain Tiger Technology that integrates multi-module terminals, full-chain algorithm libraries, and supports various data analysis and processing.

The platform adopts an advanced cloud edge architecture, supports high-performance edge computing nodes, and supports synchronous storage and analysis of data in the cloud. Not only can the sampling rate of the data (1-30kHz) be changed online, but the electrode impedance of each channel can also be measured and viewed. In addition, it also has one-click Sorting function, as well as in-depth data analysis functions such as the correlation between Spike data and Event.

In terms of data security, asymmetric encryption technology is used to protect user login information, while the user's original data uses transform domain digital watermark technology for transparent authentication, providing the most powerful guarantee for users to safely share data.

The rewritten sentence is: Brain Tiger Technology has successfully launched a "flexible brain-computer interface overall solution" for the scientific research field, which includes flexible electrodes, high-throughput neural signal acquisition systems and scientific research version of surgical robots. In addition, the "flexible brain-computer interface overall solution" for the medical market has completed key technology research and development and core device manufacturing, and is currently undergoing clinical verification and registration stages

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