Warframe: Best Catabolyst Builds

Warframe is known for having a strange arsenal of weapons for Tenno to choose from. Standard assault rifles and pistols are available to use, but there are just as many beam cannons, throwing stars, and mutated bio-weapons up for grabs. If you're willing to experiemnt, this game rewards you heavily with some truly novel items that can scale into the endgame.

Few weapons showcase this better than the Catabolyst, an Infested sidearm that can turn its magazine into an explosive grenade. Today, we'll be looking at how to get the Catabolyst and its Coda variant, explain its unique reload gimmick, and cover some builds that push this weapon to its limits.

How To Obtain The Catabolyst

The standard Catabolyst is crafted through the Bio Lab in your clan's dojo. If you aren't part of a clan, you'll need to join one or purchase the weapon with Platinum through the in-game market to obtain this weapon. The Bio Lab blueprint requires you to obtain some fairly rare materials to craft the Catabolyst, notably Scintillant .

If that upfront cost is too great, you can always wait to get the Coda Catabolyst from a Technocyte Coda Technocyte Coda later in your playthrough. You can start hunting these Infested Liches upon completing "The Hex" story quest. Defeat the Lich, then speak with Eleanor in Hollvania to purchase the weapon from her Coda weapon stock. If it's not present, wait a few days for her options to refresh.

Catabolyst Crafting Requirements
5 Scintillant	4 Ocular Stem-Root
7 Mutagen Mass	10 Stellated Necrathene
Credit Cost: 30,000	Build Time: 24 Hours

Catabolyst Stats And Features

Base Damage
	Catabolyst	Coda Catabolyst
Corrosive Beam	53	56
Corrosive Grenade	1,997	658 (x3)
Other Damage Stats
Multishot	1	1
Fire Rate	12	12
Critical Chance	11%	11%
Critical Multiplier	2.9x	2.9x
Status / Projectile	43%	50%
Misc.
Weapon Type	Pistol
Trigger Type	Auto
Accuracy	Low
Magazine	31	37
Reload Speed	1.7s	1.7s
MR Requirement	MR 11	MR 17

The Catabolyst is a secondary pistol that fires a toxic beam of energy. It has a fairly high fire rate with excellent status chance, making this a solid choice for status priming or inflicting status-based damage through Heat or Blast. Critical stats on this weapon are subpar, but you can make this weapon's critical stats much higher through its Critical Mutation Nightwave augment.

What makes the Catabolyst truly shine is its reload gimmick. Reloading this weapon will throw an explosive projectile that detonates on contact, inflicting heavy Corrosive damage to targets caught in the blast radius. If you reload from empty, this explosion deals ten times as much damage and has vastly higher critical stats. The Coda variant releases three grenades in a fan instead of just one, trading raw damage for wider area coverage.

Catabolyst Builds

You can either opt to build the Catabolyst as a traditional sidearm or lean into its grenade gimmick. We'll be showing builds that cover both specialties, although we generally recommend you stick with the former build for most content. Unless you synergize your entire loadout around the grenade mechanic, the standard beam mode will serve you better in most situations.

Beam Configuration

Forma	6 (3V, D, –, – [Exilus])
Variant	Coda Catabolyst

This build is focused on the primary fire of the Catabolyst, not the grenade effect. We'll use Galvanized Shot with Cascadia Flare to greatly increase our base damage with this weapon. Galvanized Shot will ramp up through three damage types: Corrosive, Viral, and Heat. We mod for Viral and Heat on this weapon, using Primed Heated Charge for Heat specifically to bias its proc chance.

Multishot is up next. Galvanized Diffusion with Lethal Torrent gives you more than enough multishot for the primary fire to seriously ramp up its damage. Your only damage scaling left comes from critical hits or status scaling. Either strategy will work here, but we've opted for critical hits. Galvanized Crosshairs and Primed Target Cracker should give you a solid critical chance with a high multiplier. Pair this weapon with Arcane Avenger, and you have a great workhorse for most content.

Grenade Spam

Forma	5 (3V, –, – [Exilus])
Variant	Coda Catabolyst

If you want to become a grenadier, this is the build for you. Direct damage scalars don't work on the grenade, which makes effects like Galvanized Shot ineffective here. What you can do is run Synth Charge, granting you a three times damage multiplier on your final shot. For some reason, this affects the grenades you throw on an empty magazine, substantially increasing your damage.

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If you throw your grenade and immediately use your melee weapon, Synth Charge will auto-load a round into the Catabolyst's magazine. Fire your secondary to reset your magazine, then reload again to throw another fan of grenades. You can repeat this as many times as you want.

Critical stats are also quite good on the grenade, so we'll be using Critical Mutation and Primed Target Cracker to greatly boost our critical stats. If you don't own Critical Mutation, you can run Primed Pistol Gambit instead. The rest of the build is the same as before, scaling multishot and elemental damage to make your explosions hit as hard as possible. Try to shotgun the Coda variant's grenades onto the same target to maximize your damage.

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