Path of Exile 2: Neural Catalyst Guide and How to Get

The Neural Catalyst is an item in Path of Exile 2 that enhances rings and amulets by improving mana-related stats, like maximum mana and mana regeneration.

When Should You Use Neural Catalyst?

1. You Need More Maximum Mana:

   • Use it to increase your mana pool, allowing you to cast more skills and sustain longer in fights.

2. You Need Better Mana Regeneration:

   • If your build requires frequent skill use, this Catalyst boosts your mana regeneration rate.

3. Your Gear Has Mana Stats:

   • Apply it to rings or amulets with mana-related modifiers to make those stats even stronger.

How to Use Neural Catalyst

1. Get the Catalyst:

   • The Neural Catalyst is exclusive to Breach events, where you fight hordes of monsters in alternate dimensions. These events often drop Breach-exclusive loot, including the Neural Catalyst.

2. Pick a Ring or Amulet:

   • Choose an item with maximum mana, mana regeneration, or other mana-related modifiers.

3. Apply the Catalyst:

   • Right-click Neural Catalyst, then left-click on the item.

   • Each use increases the quality of mana-related stats, up to a maximum of 20%.

Tips for Using Neural Catalyst

• Focus on Mana-Based Builds:

  • Use it on items essential for casters or builds that need a high mana pool and fast mana recovery.

• Don’t Use It on Weak Items:

  • Only apply it to high-quality rings or amulets that are critical to your build.

• Max Out the Quality:

  • Keep applying Neural Catalysts until the item reaches 20% quality for the best mana-related boost.

Example

• If you’re playing a spellcaster and need more mana for your skills:

  • Apply Neural Catalyst to an amulet with " 80 to maximum mana."

  • The Catalyst increases the mana bonus, letting you cast more spells during fights.

The Neural Catalyst is perfect for improving mana-related stats on your gear. It’s a must-have for caster builds or characters that rely heavily on mana in Path of Exile 2. Use it wisely to keep your skills flowing!

Click here to see all Catalyst types

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