How can I efficiently manipulate multiple files simultaneously in Python?

Efficient File Manipulation with Python's "with open"

Accessing multiple files simultaneously is often a critical task in Python. While using multiple "with open" statements can be tedious, Python offers elegant solutions to combine these calls with the "with" statement.

In-Line File Opening

Python versions 2.7 and above allow for in-line file opening, eliminating the need for multiple "with" statements. Simply separate file definitions with a comma within the parentheses:

with open('a', 'w') as a, open('b', 'w') as b:
    do_something()

Nesting Context Managers

In earlier versions of Python, contextlib.nested() could be used to nest context managers, but this was not recommended for working with multiple files.

ExitStack for Dynamic File Opening

In Python 3.3 onwards, contextlib.ExitStack provides a versatile option for opening a variable number of files simultaneously:

with ExitStack() as stack:
    files = [stack.enter_context(open(fname)) for fname in filenames]
    # Do something with "files"

Sequential File Processing

Depending on the use case, sequential file processing may be more appropriate than opening all files at once:

for fname in filenames:
    with open(fname) as f:
        # Process f

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