服务器经常提示mysql连接错误，有木有解决方法？

网络是联通的，因为在同一主机内，本地连接到mysql服务器，和运行环境无关，php，python连接数据库都有这种情况出现
提示

Can't connect to MySQL server on 'localhost'

下面是my.ini文件内容，已经省略注释

[client]
port=3306
[mysql]
default-character-set=utf8
[mysqld]
port=3306
basedir="E:/mysql/"
datadir="e:/mysql/data/"
default-character-set=utf8
default-storage-engine=MYISAM
sql-mode="STRICT_TRANS_TABLES,NO_AUTO_CREATE_USER,NO_ENGINE_SUBSTITUTION"
max_connections=5000
query_cache_size=52M
table_cache=4100
tmp_table_size=64M
thread_cache_size=64
myisam_max_sort_file_size=100G
myisam_sort_buffer_size=80M
key_buffer_size=256M
read_buffer_size=64K
read_rnd_buffer_size=256K
sort_buffer_size=16M
skip-innodb
innodb_additional_mem_pool_size=2M
innodb_flush_log_at_trx_commit=1
innodb_log_buffer_size=1M
innodb_buffer_pool_size=8M
innodb_log_file_size=10M
innodb_thread_concurrency=18
wait_timeout=28800
thread_concurrency=4
skip-locking
log-slow-queries = slow.log
long_query_time = 1
max_connections = 1000
max_allowed_packet = 32M
interactive_timeout = 28800

回复内容：

网络是联通的，因为在同一主机内，本地连接到mysql服务器，和运行环境无关，php，python连接数据库都有这种情况出现
提示

Can't connect to MySQL server on 'localhost'

下面是my.ini文件内容，已经省略注释

[client]
port=3306
[mysql]
default-character-set=utf8
[mysqld]
port=3306
basedir="E:/mysql/"
datadir="e:/mysql/data/"
default-character-set=utf8
default-storage-engine=MYISAM
sql-mode="STRICT_TRANS_TABLES,NO_AUTO_CREATE_USER,NO_ENGINE_SUBSTITUTION"
max_connections=5000
query_cache_size=52M
table_cache=4100
tmp_table_size=64M
thread_cache_size=64
myisam_max_sort_file_size=100G
myisam_sort_buffer_size=80M
key_buffer_size=256M
read_buffer_size=64K
read_rnd_buffer_size=256K
sort_buffer_size=16M
skip-innodb
innodb_additional_mem_pool_size=2M
innodb_flush_log_at_trx_commit=1
innodb_log_buffer_size=1M
innodb_buffer_pool_size=8M
innodb_log_file_size=10M
innodb_thread_concurrency=18
wait_timeout=28800
thread_concurrency=4
skip-locking
log-slow-queries = slow.log
long_query_time = 1
max_connections = 1000
max_allowed_packet = 32M
interactive_timeout = 28800

链接参数试一下 127.0.0.1